Article
Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules.
Human immunology - 1 Feb 1996
Sidney J, Grey H M, Southwood S, Celis E, Wentworth P A, del Guercio M F, Kubo R T, Chesnut R W, Sette A
Abstract excerpt
An HLA-A3-like supertype (minimally comprised of products from the HLA class I alleles A3, A11, A31, A*3301, and A*6801) has been defined on the basis of (a) structural similarities in the antigen-binding groove, (b) shared main anchor peptide-binding motifs, (c) the identification of peptides cross-reacting with most or all of these molecules, and (d) the definition of an A3-like supermotif that efficiently...
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