Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules.

Article

Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1996

Sidney J, Southwood S, del Guercio M F, Grey H M, Chesnut R W, Kubo R T, Sette A

Abstract excerpt

The HLA-B7-like binding supertype includes several different HLA-B molecules. Herein, the primary and secondary anchor specificities of the five most common HLA-B7-like molecules (B*0702, B*3501, B51, B*5301, and B*5401) were defined by the use of molecular binding assays, analogue peptides, and...

Topics

Alleles
Amino Acid Sequence
Binding Sites
HLA-B Antigens
HLA-B7 Antigen
Humans
In Vitro Techniques
Ligands
Molecular Sequence Data
Oligopeptides
Protein Binding
Protein Engineering

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