Article
Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes.
Molecular immunology - 1 Oct 2013
Niu Ling, Cheng Hao, Zhang Shihong, Tan Shuguang, Zhang Yudan, Qi Jianxun, Liu Jun, Gao George F
Abstract excerpt
High polymorphism is one of the most important features of human leukocyte antigen (HLA) alleles, which were initially classified by serotyping but have recently been re-grouped into supertypes according to their peptide presentation properties. Two relatively prevalent HLA alleles HLA-A*6801 and HLA-A*6802, are classified into the same serotype HLA-A68. However, based on their distinct peptide-binding...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.