Article
Induction of membrane ruffling by growth factors in morphologically TPA-resistant Balb/c3T3 TR4 cells.
Cell structure and function - 1 Apr 1994
Enomoto T, Asano Y
Abstract excerpt
To investigate the biological characteristics of a Balb/c3T3 variant TR4 clone which is morphologically resistant to TPA and hypersensitive to v-src induced metastasis, we compared the responsiveness of the variant and its parent cells to growth factor-induced membrane ruffling. When the confluent cells were stimulated with PDGF, membrane ruffling was rapidly induced in TR4 but not in the parent cell cultures. In...
Topics
- 3T3 Cells
- Animals
- Cell Line
- Cell Membrane
- Drug Resistance
- Fibroblast Growth Factor 1
- Fibroblast Growth Factor 2
- Fibroblasts
- Growth Substances
- Insulin
- Insulin-Like Growth Factor I