Article
In vitro exposure of polyoma-virus-transformed cells to laminin augments their in vivo malignancy phenotype.
Invasion & metastasis - 1 Jan 1993
Katz B Z, Witz I P
Abstract excerpt
The aim of this study was to assess the influence of the extracellular matrix (ECM) proteins laminin and fibronectin on the malignancy phenotype of BALB/c 3T3 cells transformed in vitro with polyoma virus (PyV). The in vitro incubation of low-tumorigenicity cells from a PyV-transformed clone on laminin-coated plates, and to a lesser extent on fibronectin-coated ones, increased their ability to form experimental...
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