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Article

[The characteristics of the internalization of normal and mutant receptors for the growth factor released by thrombocytes].

Tsitologiia - 1 Jan 1992

D'iakonova M Iu, Sorkin A D, Nikol'skiĭ N N

Abstract excerpt

The platelet-derived growth factor (PDGF) is a major mitogen in serum for connective tissue derived cells in culture. The influence of receptor structure on the ability of PDGF receptor to be internalized was studied using cell lines transfected with different PDGF-receptor constructions. CHO cell lines expressing either normal PDGF receptor (CHO wt cells) or truncated PDGF receptor, lacking all but 19 amino...

Topics

Animals
Cell Line
Cells, Cultured
Chloroquine
Cricetinae
Cricetulus
Endocytosis
Female
Fluorescent Antibody Technique
Iodine Radioisotopes
Ligands
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovary

Platelet-Derived Growth Factor

Receptors, Platelet-Derived Growth Factor

Recombinant Proteins

Time Factors

Source

Identifiers

PMID: 1293877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1293877-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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[The characteristics of the internalization of normal and mutant receptors for the growth factor released by thrombocytes].PMID 1293877Read ↗

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