Article
Some cellular and molecular characteristics of high and low tumorigenicity variants of polyoma-virus transformed cells.
Molecular immunology - 1 Dec 1990
Berko-Flint Y, Fridman W H, Grossman-Atlas E, Kimchi N, Ben-Baruch A L, Moss S, Teillaud J L, Witz I P, Ran M
Abstract excerpt
We analyzed several cellular and molecular properties of BALB/c 3T3 cellular clones transformed in vitro with polyoma virus and exhibiting a high or low tumorigenicity phenotype. We also analyzed the same clones after a single in vivo passage in syngeneic mice. This passage invariably induced and...
Topics
- Animals
- Antigens, Differentiation
- Antigens, Polyomavirus Transforming
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Chromosome Mapping
- Clone Cells
- DNA, Viral
- Genetic Variation
- Immune Tolerance
