Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential tyrosine-specific phosphorylation of integrin in Rous sarcoma virus transformed cells with differing transformed phenotypes.

Oncogene - 1 Sept 1990

Horvath A R, Elmore M A, Kellie S

Abstract excerpt

We have investigated the localization and phosphorylation of the fibronectin receptor in chick embryo fibroblasts transformed either by wild-type Prague C strain Rous sarcoma virus, which induces a rounded, less adhesive phenotype with a loss of surface fibronectin and gross cytoskeletal changes, or transformed by rASV2234.3, a variant which induces a flat, adhesive morphology with the retention of surface...

Topics

Amino Acids
Animals
Avian Sarcoma Viruses
Cell Transformation, Viral
Chick Embryo
Fibronectins
Fluorescent Antibody Technique
Integrins
Membrane Proteins
Phenotype
Phosphorylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein-Tyrosine Kinases

Proto-Oncogene Proteins pp60(c-src)

Source

Identifiers

PMID: 1699197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1699197-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential tyrosine-specific phosphorylation of integrin in Rous sarcoma virus transformed cells with differing transformed phenotypes.PMID 1699197Read ↗

Forced expression of tropomyosin 2 or 3 in v-Ki-ras-transformed fibroblasts results in distinct phenotypic effects.Semantic proximity Read ↗

Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells.Semantic proximity Read ↗

Glycoprotein tyrosine phosphorylation in Rous sarcoma virus-transformed chicken embryo fibroblasts.Semantic proximity Read ↗

v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts.Semantic proximity Read ↗

A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src.Semantic proximity Read ↗

v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions.Semantic proximity Read ↗

Src kinase has a central role in in vitro cellular internalization of Staphylococcus aureus.Semantic proximity Read ↗

Induction of β3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling PathwaySemantic proximity Read ↗

Loss of transformed phenotype upon senescence of Rous sarcoma virus-infected chicken neuroretinal cells.Semantic proximity Read ↗

pp60v-src transformation of rat cells but not chicken cells strongly correlates with low-affinity phosphopeptide binding by the SH2 domain.Semantic proximity Read ↗

A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts.Semantic proximity Read ↗

ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.