Article
RNA-Regulated TRA-1 nuclear export controls sexual fate.
Developmental cell - 1 Oct 2001
Segal S P, Graves L E, Verheyden J, Goodwin E B
Abstract excerpt
TRA-1, a member of the GLI family of transcription factors, is required for C. elegans female development. We find that TRA-1 has a sex-specific distribution consistent with its role in female development: nuclear TRA-1 is higher in hermaphrodite intestines and in specific germline regions than in males. TRA-1 patterns rely on nuclear export since treatment with leptomycin B, a CRM1-dependent export inhibitor,...
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