Isolation of dominant XO-feminizing mutations in Caenorhabditis elegans: new regulatory tra alleles and an X chromosome duplication with implications for primary sex determination.

doi:10.1093/genetics/141.2.527

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Article

Isolation of dominant XO-feminizing mutations in Caenorhabditis elegans: new regulatory tra alleles and an X chromosome duplication with implications for primary sex determination.

Genetics - 1 Oct 1995

Hodgkin J, Albertson D G

Abstract excerpt

A strain of Caenorhabditis elegans was constructed that permits selection of dominant or sex-linked mutations that transform XO animals (normally male) into fertile females, using a feminizing mutation, tra-2(e2046gf), which by itself does not sexually transform XO males. Twenty-three mutations w...

Topics

Animals
Caenorhabditis elegans
Chromosome Mapping
Female
Fertility
Genes, Dominant
Genes, Helminth
Genes, Lethal
In Situ Hybridization, Fluorescence
Male
Mutation
Sex Differentiation
X Chromosome

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