Article
The tra-1 gene determines sexual phenotype cell-autonomously in C. elegans.
Cell - 21 Dec 1990
Hunter C P, Wood W B
Abstract excerpt
The tra-1 gene plays a central role in C. elegans sex determination. XX animals develop as hermaphrodites when tra-1 is active and as males when it is not. By analyzing a large number of tra-1 genetic mosaics we have shown that, with the expected exception of vulval induction by the hermaphrodite gonad, tra-1 functions cell-autonomously, consistent with a role as an intracellular component of a signaling pathway....
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