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Article

Molecular cloning and duplication of the nematode sex-determining gene tra-1.

Genetics - 1 Mar 1993

Hodgkin J

Abstract excerpt

The autosomal sex-determining gene tra-1 plays a major role in controlling sexual phenotype in the nematode Caenorhabditis elegans. This gene is the terminal global regulator in a well-characterized cascade of sex-determining genes. It governs all aspects of somatic sexual differentiation, and it also has important functions in governing germ-line differentiation. Previous genetic analyses have led to the...

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Identifiers

PMID: 8384144
DOI: 10.1093/genetics/133.3.543
PMCID: PMC1205342

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