Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative genetics of sex determination: masculinizing mutations in Caenorhabditis briggsae.

Genetics - 1 Mar 2008

Kelleher Danielle F, de Carvalho Carlos Egydio, Doty Alana V, Layton Marnie, Cheng Andy T, Mathies Laura D, Pilgrim Dave, Haag Eric S

Abstract excerpt

The nematodes Caenorhabditis elegans and C. briggsae independently evolved self-fertile hermaphroditism from gonochoristic ancestors. C. briggsae has variably divergent orthologs of nearly all genes in the C. elegans sex determination pathway. Their functional characterization has generally relie...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis
Share to Cell Lineage
Share to Germ Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gonads

Share to Helminth Proteins

Share to Mutant Proteins

Share to Sex Determination Processes

Share to Zygote

Source

Open in PubMed Open full text

Identifiers

PMID: 18245372
DOI: 10.1534/genetics.107.073668
PMCID: PMC2278099

Genes

TRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18245372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative genetics of sex determination: masculinizing mutations in Caenorhabditis briggsae.PMID 18245372Read ↗

Genetic flexibility in the convergent evolution of hermaphroditism in Caenorhabditis nematodes.Semantic proximity Read ↗

Extragenic suppressors of a dominant masculinizing her-1 mutation in C. elegans identify two new genes that affect sex determination in different ways.Semantic proximity Read ↗

The evolution of nematode sex determination: C. elegans as a reference point for comparative biologySemantic proximity Read ↗

Molecular analysis of tra-2, a sex determining gene in C.elegans.Semantic proximity Read ↗

Rewiring the Sex-Determination Pathway During the Evolution of Self-Fertility.Semantic proximity Read ↗

The tra-1 gene determines sexual phenotype cell-autonomously in C. elegans.Semantic proximity Read ↗

Caenorhabditis tropicalis followed a unique evolutionary path to self-fertility.Semantic proximity Read ↗

Interspecies comparison reveals evolution of control regions in the nematode sex-determining gene tra-2.Semantic proximity Read ↗

New tools for investigating the comparative biology of Caenorhabditis briggsae and C. elegans.Semantic proximity Read ↗

Somatic sex determinationSemantic proximity Read ↗

Dominant feminizing mutations implicate protein-protein interactions as the main mode of regulation of the nematode sex-determining gene tra-1.Semantic proximity Read ↗

Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.