Sequenced alleles of the Caenorhabditis elegans sex-determining gene her-1 include a novel class of conditional promoter mutations.

doi:10.1093/genetics/138.2.317

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Article

Sequenced alleles of the Caenorhabditis elegans sex-determining gene her-1 include a novel class of conditional promoter mutations.

Genetics - 1 Oct 1994

Perry M D, Trent C, Robertson B, Chamblin C, Wood W B

Abstract excerpt

In the control of Caenorhabditis elegans sex determination, the her-1 gene must normally be activated to allow male development of XO animals and deactivated to allow hermaphrodite development of XX animals. The gene is regulated at the transcriptional level and has two nested male-specific transcripts. The larger of these encodes a small, novel, cysteine-rich protein responsible for masculinizing activity. Of...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Codon
DNA, Helminth
Exons
Female
Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Helminth

Helminth Proteins

Male

Molecular Sequence Data

Mutation

Point Mutation

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 7828816
DOI: 10.1093/genetics/138.2.317
PMCID: PMC1206151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7828816-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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