Article
Molecular approach to rapid assessment of p53 tumor suppressor mutations in esophageal tumors from stained histological slides.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 1994
Whetsell L H, Ringer D P, Schaefer F V
Abstract excerpt
The analysis of the tumor suppressor gene, p53, is of fundamental importance in prognosis and staging in many cancers; however, the molecular techniques required to analyze this gene have been expensive, time consuming, and unrelatable to the histological appearance of the samples. This research...
Topics
- Adenoma
- Base Sequence
- DNA Probes
- Esophageal Neoplasms
- Genes, p53
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Staining and Labeling
- Tumor Cells, Cultured