Article
Molecular approach to rapid assessment of p53 tumor suppressor mutations in esophageal tumors from stained histological slides.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 1994
Whetsell L H, Ringer D P, Schaefer F V
Abstract excerpt
The analysis of the tumor suppressor gene, p53, is of fundamental importance in prognosis and staging in many cancers; however, the molecular techniques required to analyze this gene have been expensive, time consuming, and unrelatable to the histological appearance of the samples. This research explored one model of clinically testing for specific mutations in the p53 gene by scraping selected areas of stained...
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