The denatured state (the other half of the folding equation) and its role in protein stability.

Abstract excerpt

Experimental studies of the physical interactions that stabilize protein structure are complicated by the fact that proteins do not unfold to a simple reference state. When their folded structure breaks down, protein chains do not become random coils. Instead, they enter a poorly understood ensem...

Topics

• Mutation
• Protein Conformation
• Protein Denaturation
• Protein Folding
• Proteins
• Thermodynamics