Article
C-kit gene is expressed by skin mast cells in embryos but not in puppies of Wsh/Wsh mice: age-dependent abolishment of c-kit gene expression.
Blood - 15 Jun 1994
Yamazaki M, Tsujimura T, Morii E, Isozaki K, Onoue H, Nomura S, Kitamura Y
Abstract excerpt
The Wsh is a mutant allele at the W (c-kit) locus of mice, but no significant abnormalities are found at the coding region of the Wsh allele. Since cultured mast cells derived from the spleen of Wsh/Wsh mice do not express messenger RNA (mRNA) of c-kit, we studied the interrelation between the nu...
Topics
- Age Factors
- Animals
- Animals, Newborn
- Base Sequence
- Female
- Gene Expression Regulation
- Mast Cells
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Mutation
- Pregnancy
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-kit
- Proto-Oncogenes
- RNA, Messenger
- Receptor Protein-Tyrosine Kinases
- Receptors, Colony-Stimulating Factor