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Article

Interstitial cells of Cajal in Wsh/Wsh c-kit mutant mice.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi - 1 Jan 2020

Iino Satoshi, Horiguchi Satomi, Horiguchi Kazuhide, Hashimoto Takashi

Abstract excerpt

The c-Kit receptor tyrosine kinase regulates the development and differentiation of several progenitor cells. In the gastrointestinal (GI) tract, the c-Kit regulates the development of the interstitial cells of Cajal (ICC) that are responsible for motility regulation of the GI musculature. W-sash (Wsh) is an inversion mutation upstream of the c-kit promoter region that affects a key regulatory element, resulting...

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Identifiers

PMID: 33132281
DOI: 10.1540/jsmr.56.58
PMCID: PMC7596356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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