Article
Developmental expression of c-kit, a proto-oncogene encoded by the W locus.
Development (Cambridge, England) - 1 Aug 1990
Orr-Urtreger A, Avivi A, Zimmer Y, Givol D, Yarden Y, Lonai P
Abstract excerpt
Developmental expression of the c-kit proto-oncogene, a receptor tyrosine kinase encoded by the W locus, was investigated by in situ hybridization in normal mouse embryos. Early after implantation transcripts were detectable only in the maternal placenta (6 1/2-7 1/2 days p.c.). Subsequently (8 1/2 days p.c.) numerous ectodermal (neural tube, sensory placodes) and endodermal (embryonic gut) derivatives expressed...
Topics
- Alleles
- Animals
- Central Nervous System
- Ectoderm
- Embryo, Mammalian
- Endoderm
- Female
- Gene Expression
- Germ Cells
- Male
- Mice
- Mice, Inbred Strains