Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation.

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Article

Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation.

Blood - 15 May 1993

Tsujimura T, Koshimizu U, Katoh H, Isozaki K, Kanakura Y, Tono T, Adachi S, Kasugai T, Tei H, Nishimune Y

Abstract excerpt

The W locus of mice encodes the c-kit receptor tyrosine kinase. Heterozygous WJic/+ and Wn/+ mice and homozygous Wf/Wf mice were similar in appearance; all of them have large depigmented areas lacking any well-defined pattern. The WJic, Wn, and Wf mutant alleles were characterized and their molec...

Topics

Adenosine Triphosphate
Alleles
Animals
Base Sequence
Cell Survival
Cells, Cultured
Crosses, Genetic
Erythrocyte Count
Fibroblasts
Genotype
Hair Color
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homozygote

Leukocyte Count

Mast Cells

Mice

Mice, Inbred C57BL

Mice, Mutant Strains

Source

Open in PubMed

Identifiers

PMID: 7683920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7683920-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation.PMID 7683920Read ↗

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