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Article

Gene mapping in a murine cell line by immunoselection with cytotoxic T lymphocytes.

Genomics - 15 Jan 1994

Zuberi A R, Dudley M E, Christianson G J, Roopenian D C

Abstract excerpt

Minor histocompatibility (H) loci encode alloantigens that are recognized by cytotoxic T (Tc) lymphocytes. A (C57BL/10 x 129)F1-derived transformed lymphocyte cell line was immunoselected in vitro with cloned Tc cells that were specific for H-3aa, a Chromosome 2-encoded minor H antigen. This cell line is heterozygous at H-3a (former symbol, Cd-1) and other loci. Three groups of antigen-loss variants were...

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Identifiers

PMID: 7514566
DOI: 10.1006/geno.1994.1058

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