Gene mapping in a murine cell line by immunoselection with cytotoxic T lymphocytes.

doi:10.1006/geno.1994.1058

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Article

Gene mapping in a murine cell line by immunoselection with cytotoxic T lymphocytes.

Genomics - 15 Jan 1994

Zuberi A R, Dudley M E, Christianson G J, Roopenian D C

Abstract excerpt

Minor histocompatibility (H) loci encode alloantigens that are recognized by cytotoxic T (Tc) lymphocytes. A (C57BL/10 x 129)F1-derived transformed lymphocyte cell line was immunoselected in vitro with cloned Tc cells that were specific for H-3aa, a Chromosome 2-encoded minor H antigen. This cell line is heterozygous at H-3a (former symbol, Cd-1) and other loci. Three groups of antigen-loss variants were...

Topics

Animals
Antigens, CD
Antigens, CD1
Cell Line, Transformed
Chromosome Mapping
Cytotoxicity, Immunologic
Female
Genes
Heterozygote
Karyotyping
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mutation

Selection, Genetic

Sequence Deletion

T-Lymphocytes, Cytotoxic

beta 2-Microglobulin

Source

Open in PubMed

Identifiers

PMID: 7514566
DOI: 10.1006/geno.1994.1058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7514566-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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