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Article

A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen.

Immunogenetics - 1 Aug 2003

Luedtke Brianna, Pooler Laura M, Choi Eun Young, Tranchita Angela M, Reinbold Corbett J A, Brown Aaron C, Shaffer Daniel J, Roopenian Derry C, Malarkannan Subramaniam

Abstract excerpt

Minor histocompatibility antigens (minor H antigen) elicit strong T-cell-mediated responses during both graft rejection and graft versus leukemia (GvL) among MHC-matched individuals (where MHC is major histocompatibility complex). Employing expression-cloning methodology, we have identified a cDNA clone, MI-35, encoding the immunodominant H4b minor H antigen within the classical mouse H4 complex. The minimal...

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PMID: 12845499
DOI: 10.1007/s00251-003-0581-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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