A genetic analysis of human minor histocompatibility antigens demonstrates Mendelian segregation independent of HLA.

doi:10.1007/BF00190897

Back to search

Article

A genetic analysis of human minor histocompatibility antigens demonstrates Mendelian segregation independent of HLA.

Immunogenetics - 1 Jan 1993

Schreuder G M, Pool J, Blokland E, van Els C, Bakker A, van Rood J J, Goulmy E

Abstract excerpt

An analysis of the genetic traits of human minor histocompatibility (mH) antigens is, unlike with inbred mice, rather complicated. Moreover, the fact that mH antigens are recognized in the context of MHC molecules creates an additional complication for reliable segregation analysis. To gain insig...

Topics

Alleles
Clone Cells
Gene Frequency
Genes, Dominant
Genetic Linkage
HLA Antigens
Humans
Lod Score
Minor Histocompatibility Loci
T-Lymphocytes, Cytotoxic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.