Article
Simultaneous immunoselection in vitro for H-Y or H-2D antigen-loss variants of a mouse-derived B cell line.
Mutation research - 13 Sept 1996
King T R
Abstract excerpt
Cytotoxic T lymphocytes (CTL) specifically reactive with the male transplantation antigen (H-Y) were used to immunoselect in vitro for antigen loss among cells from an Abelson murine leukemia virus (AbMuLV) transformed lymphoblastoid cell line. Numerous variant cell clones were recovered that had lost expression of either H-Y or the restricting major histocompatibility class I molecule, H-2D. In all experiments,...
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