Article
The genetic origin of minor histocompatibility antigens.
Immunogenetics - 1 Jan 1993
Roopenian D C, Christianson G J, Davis A P, Zuberi A R, Mobraaten L E
Abstract excerpt
The purpose of this study was to elucidate the genetic origin of minor histocompatibility (H) antigens. Toward this end common inbred mouse strains, distinct subspecies, and species of the subgenus Mus were examined for expression of various minor H antigens. These antigens were encoded by the classical minor H loci H-3 and H-4 or by newly identified minor H antigens detected as a consequence of mutation. Both...
Topics
- Animals
- Biological Evolution
- Chromosome Mapping
- Epitopes
- Genetic Linkage
- Lymphocyte Culture Test, Mixed
- Mice
- Mice, Inbred Strains
- Minor Histocompatibility Antigens
- Minor Histocompatibility Loci
- Mutation