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Article

Loss of heterozygosity and mitotic linkage maps in the mouse.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1991

Henson V, Palmer L, Banks S, Nadeau J H, Carlson G A

Abstract excerpt

Loss of heterozygosity is a significant oncogenetic mechanism and can involve a variety of mechanisms including chromosome loss, deletion, and homologous interchromosomal mitotic recombination. Analysis of H-2 antigen-loss variants from heterozygous murine cell lines provides an experimental system to estimate the relative contributions of different mechanisms for allele loss and to compare the chromosomal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1677769
DOI: 10.1073/pnas.88.15.6486
PMCID: PMC52110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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