Loss of heterozygosity and mitotic linkage maps in the mouse.

doi:10.1073/pnas.88.15.6486

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Article

Loss of heterozygosity and mitotic linkage maps in the mouse.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1991

Henson V, Palmer L, Banks S, Nadeau J H, Carlson G A

Abstract excerpt

Loss of heterozygosity is a significant oncogenetic mechanism and can involve a variety of mechanisms including chromosome loss, deletion, and homologous interchromosomal mitotic recombination. Analysis of H-2 antigen-loss variants from heterozygous murine cell lines provides an experimental syst...

Topics

Alleles
Animals
Base Sequence
Cell Line
Chromosome Mapping
Crosses, Genetic
DNA Probes
Female
Genetic Linkage
Genetic Variation
H-2 Antigens
Heterozygote
Homozygote
Male
Meiosis
Mice
Mice, Inbred Strains
Mitosis

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