Article
[Proliferative activity and p53 expression in transitional cell carcinoma of the urinary bladder].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1993
Offner F A, Schäfer G, Hittmair A, Ofner D, Grünewald K, Weyrer K, Mattern D, Eberle J, Mikuz G, Feichtinger H
Abstract excerpt
Mutations of the p53 gene are important mechanisms in malignant transformation and are associated with dysregulation of normal cell growth. In the present study the expression of mutated p53-protein and proliferating cell nuclear antigen (PCNA) was investigated in a series of 31 human transitiona...
Topics
- Analysis of Variance
- Antigens, Neoplasm
- Carcinoma in Situ
- Carcinoma, Transitional Cell
- Cell Division
- Gene Expression
- Genes, p53
- Humans
- Immunohistochemistry
- Mutation
- Nuclear Proteins
- Proliferating Cell Nuclear Antigen
- Tumor Suppressor Protein p53
- Urinary Bladder Neoplasms