Article
Base 2661 in Escherichia coli 23S rRNA influences the binding of elongation factor Tu during protein synthesis in vivo.
European journal of biochemistry - 18 Dec 1991
Tapio S, Isaksson L A
Abstract excerpt
The binding of the EF-Tu.GTP.aminoacyl-tRNA ternary complex (EF, elongation factor) to the ribosome is known to be strengthened by a 2661G-to-C mutation in 23S ribosomal RNA, whereas the binding to normal ribosomes is weakened if the factor is in an appropriate mutant form (Aa). In this report we...
Topics
- Alleles
- Base Sequence
- Binding Sites
- Codon
- Escherichia coli
- Escherichia coli Proteins
- Genotype
- Peptide Chain Elongation, Translational
- Peptide Elongation Factor Tu
- Plasmids
- RNA, Ribosomal, 23S
- Ribosomal Protein S9
- Ribosomes
- Suppression, Genetic