Article
The clastogenic and mutagenic effects of ascorbigen and 1'-methylascorbigen.
Mutation research - 1 Jan 2000
Musk S R, Preobrazhenskaya M N, Belitsky G A, Korolev A M, Lytcheva T A, Khitrovo I A, Johnson I T
Abstract excerpt
Ascorbigen, which occurs naturally in the human diet, and a synthetic analogue (1'-methylascorbigen), were assayed for cytotoxic and clastogenic activities in a SV40-transformed Indian Muntjac cell line (SVM), and for mutagenic activity in the Ames test using Salmonella typhimurium strains TA98 a...
Topics
- Animals
- Ascorbic Acid
- Cell Line
- Cell Survival
- Chromosome Aberrations
- Deer
- Indoles
- Mutagenicity Tests
- Mutagens
- Mutation
- Salmonella typhimurium
- Sister Chromatid Exchange