Article
Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin.
Drug and chemical toxicology - 1 Jan 2008
Bandyopadhyay Atrayee, Ghoshal Sarbani, Mukherjee Anita
Abstract excerpt
Low-calorie sweeteners are chemicals that offer the sweetness of sugar without the calories. Consumers are increasingly concerned about the quality and safety of many products present in the diet, in particular, the use of low-calorie sweeteners, flavorings, colorings, preservatives, and dietary supplements. In the present study, we evaluated the mutagenicity of the three low-calorie sweeteners in the...
Topics
- Administration, Oral
- Animals
- Aspartame
- Bone Marrow Cells
- DNA Damage
- DNA, Bacterial
- Dose-Response Relationship, Drug
- Male
- Mice
- Mutagens
- Mutation
- Saccharin
- Salmonella typhimurium
- Sweetening Agents
- Thiazines