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Vitamin C (Ascorbate) and Redox Topics in Cancer

13 Jul 2021

Abstract excerpt

Significance: Vitamin C (ascorbate), in regard to its effectiveness against malignancies, has had a controversial history in cancer treatment. It has been shown that in vitro and in vivo anticancer efficacy of ascorbate relies on its pro-oxidant effect mainly from an increased generation of reactive oxygen species (ROS). A growing understanding of its anticancer activities and pharmacokinetic properties has...

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PMID: 34254829
DOI: 10.1089/ars.2020.8233

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