Article
[Anticlastogenic activity of apo-carotene in vivo].
Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2000
Durnev A D, Tiurina L S, Guseva N V, Oreshchenko A V, Seredinin S B
Abstract excerpt
The method of chromosome aberration scoring in the bone marrow cells of C57BL/6 mice was used to study the influence of apo-carotene (AC) on the clastogenic effect of intraperitoneal injections of the following two mutagens: cyclophosphamide (CP) in a dose of 30 mg/kg and dioxidine (DN) in a dose...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- Carotenoids
- Chromosome Aberrations
- Cyclophosphamide
- Drug Interactions
- Injections, Intraperitoneal
- Male
- Mice
- Mice, Inbred C57BL
- Mutagens
- Mutation
- Quinoxalines