Article
Modulatory effects of a tannin fraction isolated from Terminalia arjuna on the genotoxicity of mutagens in Salmonella typhimurium.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Dec 2000
Kaur S J, Grover I S, Kumar S
Abstract excerpt
A fraction isolated from Terminalia arjuna was studied for its antimutagenic effect against 4-nitro-o-phenylenediamine (NPD) in TA98, sodium azide in TA100 and 2-aminofluorene (2AF, S9-dependent), a promutagen, in both TA98 and TA 100 tester strains of Salmonella typhimurium using the Ames assay. The fraction inhibited the mutagenicity of 2AF very significantly in both strains while the revertant colonies induced...
Topics
- Antimutagenic Agents
- Chromatography, Thin Layer
- Fluorenes
- Magnetic Resonance Spectroscopy
- Medicine, Ayurvedic
- Mutagenicity Tests
- Mutagens
- Mutation
- Phenylenediamines
- Phytotherapy
- Plants, Medicinal
- Rosales
- Salmonella typhimurium
- Sodium Azide
- Spectrophotometry, Infrared
- Spectrophotometry, Ultraviolet
- Tannins