Article
Genetic toxicology of folpet and captan.
Critical reviews in toxicology - 1 Jul 2010
Arce Gail T, Gordon Elliot B, Cohen Samuel M, Singh Pramila
Abstract excerpt
Folpet and captan are fungicides whose genotoxicity depends on their chemical reaction with thiols. Multiple mutagenicity tests have been conducted on these compounds due to their positive activity in vitro and their association with gastrointestinal tumors in mice. A review of the collective data shows that these compounds have in vitro mutagenic activity but are not genotoxic in vivo. This dichotomy is...
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