Sequence variants of human T-cell lymphotropic virus type I from patients with tropical spastic paraparesis and adult T-cell leukemia do not distinguish neurological from leukemic isolates.

Abstract excerpt

We have amplified and sequenced DNA in the envelope (env) and long terminal repeat (LTR) regions of human T-cell lymphotropic virus type I (HTLV-I) proviruses from the peripheral blood of 10 HTLV-I-seropositive patients with tropical spastic paraparesis (TSP) and two patients with adult T-cell le...

Topics

• Adult
• Base Sequence
• Cloning, Molecular
• Female
• Genes, Viral
• Genetic Variation
• Human T-lymphotropic virus 1
• Humans
• Leukemia-Lymphoma, Adult T-Cell
• Molecular Sequence Data
• Oligonucleotide Probes