Serum concentration and genetic polymorphism in the 5'-untraslated region of VEGF is not associated with susceptibility to HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I infected individuals.

doi:10.1016/j.jns.2004.01.009

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Article

Serum concentration and genetic polymorphism in the 5'-untraslated region of VEGF is not associated with susceptibility to HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I infected individuals.

Journal of the neurological sciences - 15 Apr 2004

Saito Mineki, Usuku Koichiro, Nobuhara Yasuyuki, Matsumoto Wataru, Kodama Daisuke, Sabouri Amir H, Izumo Shuji, Arimura Kimiyoshi, Osame Mitsuhiro

Abstract excerpt

HTLV-I- associated myelopathy/tropical spastic paraparesis (HAM/TSP) is one outcome of human T-cell lymphotropic virus type I (HTLV-I) infection. It remains unknown why the majority of infected people remain healthy whereas only approximately 2-3% of infected individuals develop the disease. Recently, it has been reported that increased plasma concentrations of VEGF were significantly related to high ATL cell...

Topics

5' Untranslated Regions
Antibodies, Viral
Carrier State
Genetic Predisposition to Disease
Human T-lymphotropic virus 1
Humans
Paraparesis, Tropical Spastic
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Proviruses
Vascular Endothelial Growth Factor A

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PMID: 15050452
DOI: 10.1016/j.jns.2004.01.009

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