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Article

An ionizing radiation-sensitive mutant of CHO cells: irs-20. I. Isolation and initial characterization.

Radiation research - 1 Nov 1993

Stackhouse M A, Bedford J S

Abstract excerpt

We have isolated a stable mutant of CHO cells, designated irs-20, that is hypersensitive to ionizing radiation. The selection system was designed to select for mutants unable to proliferate at the low dose rate of 0.06 Gy per hour, a dose rate that has little influence on the effect of radiation on the cell cycle of wild-type cells during 1- to 2-week exposures. The irs-20 mutant cells irradiated continuously at...

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PMID: 7504309

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