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Article

Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells.

DNA repair - 12 Jul 2005

Hinz John M, Yamada N Alice, Salazar Edmund P, Tebbs Robert S, Thompson Larry H

Abstract excerpt

Unrepaired DNA double-strand breaks (DSBs) produced by ionizing radiation (IR) are a major determinant of cell killing. To determine the contribution of DNA repair pathways to the well-established cell cycle variation in IR sensitivity, we compared the radiosensitivity of wild-type CHO cells to mutant lines defective in nonhomologous end joining (NHEJ), homologous recombination repair (HRR), and the Fanconi...

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Identifiers

PMID: 15951249
DOI: 10.1016/j.dnarep.2005.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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