Article
A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity.
Mutation research - 8 Aug 1996
Busch D B, Zdzienicka M Z, Natarajan A T, Jones N J, Overkamp W J, Collins A, Mitchell D L, Stefanini M, Botta E, Albert R B, Liu N, White D A, van Gool A J, Thompson L H
Abstract excerpt
A new mitomycin C (MMC)-sensitive rodent line, UV40, has been identified in the collection of ultraviolet light- (UV-) sensitive mutants of Chinese hamster ovary (CHO) cells isolated at the previous Facility for Automated Experiments in Cell Biology (FAECB). It was isolated from an UV mutant hunt using mutagenesis of AA8 cells with the DNA intercalating frameshift mutagen ICR170. It is complemented by CHO-UV-1,...
Topics
- Adenine
- Aminoacridines
- Animals
- CHO Cells
- Cell Adhesion
- Cell Line
- Cell Survival
- Chromosome Aberrations
- Cricetinae
- DNA Replication
- Genetic Complementation Test