Article
Thermal radiosensitization in heat- and radiation-sensitive mutants of CHO cells.
International journal of radiation biology - 1 Aug 1993
Kampinga H H, Kanon B, Konings A W, Stackhouse M A, Bedford J S
Abstract excerpt
Recently, it has been hypothesized (Iliakis and Seaner 1990) that DNA double-strand break (dsb) repair proficiency is a prerequisite for heat radiosensitization on the basis of the finding that the radiosensitive and dsb-repair-deficient mutant xrs-5 cell line shows no significant heat-induced radiosensitization (not even for severe heat doses), whereas their wildtype counterpart (CHO) did show such an effect. In...
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