An ionizing radiation-sensitive mutant of CHO cells: irs-20. III. Chromosome aberrations, DNA breaks and mitotic delay.

doi:10.1080/09553009414550661

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Article

An ionizing radiation-sensitive mutant of CHO cells: irs-20. III. Chromosome aberrations, DNA breaks and mitotic delay.

International journal of radiation biology - 1 May 1994

Stackhouse M A, Bedford J S

Abstract excerpt

The ionizing radiation-sensitive mutant of CHO cells, irs-20, showed a defect in the rate and extent of rejoining of gamma-ray-induced DNA double-strand breaks (dsbs) compared with the parental CHO cells as measured using pulsed-field gel electrophoresis. Virtually all rejoined in wild-type cells...

Topics

Animals
CHO Cells
Cell Cycle
Chromosome Aberrations
Cricetinae
DNA
DNA Damage
Gamma Rays
Mitosis
Mutation
Phenotype
Radiation Tolerance

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