Article
Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant.
International journal of radiation biology - 1 Jun 1990
Iliakis G E, Okayasu R
Abstract excerpt
The response to ionizing radiation of synchronized and plateau-phase populations of xrs-5 cells was studied at the DNA and cellular level. Induction and repair of DNA double-strand breaks (dsb) were measured by the non-unwinding filter elution technique. Biphasic survival curves were obtained thr...
Topics
- Animals
- Cell Cycle
- Cell Line
- Cell Survival
- Cricetinae
- DNA
- DNA Damage
- DNA Repair
- In Vitro Techniques
- Mutation
- Radiation Tolerance
