Article
Retinoblastoma gene mutations in primary human prostate cancer.
The Prostate - 1 Dec 1995
Kubota Y, Fujinami K, Uemura H, Dobashi Y, Miyamoto H, Iwasaki Y, Kitamura H, Shuin T
Abstract excerpt
Structural alterations in the entire coding regions (exons 1 to 27) of the retinoblastoma (RB) gene in primary human prostate cancers were investigated, using polymerase chain reaction and single strand conformational polymorphism analysis of RNA. Of 25 samples obtained from patients, four (16.4%...
Topics
- Adenocarcinoma
- Base Sequence
- DNA Primers
- DNA, Neoplasm
- Exons
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Prostate
- Prostatic Neoplasms
- RNA, Neoplasm