Androgen receptor gene mutations in human prostate cancer.

doi:10.1016/0960-0760(93)90316-o

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Article

Androgen receptor gene mutations in human prostate cancer.

The Journal of steroid biochemistry and molecular biology - 1 Dec 1993

Suzuki H, Sato N, Watabe Y, Masai M, Seino S, Shimazaki J

Abstract excerpt

To investigate the structural abnormality of the androgen receptor (AR) in human prostate cancers, exons B-H encoding DNA- and hormone-binding domains were examined by single-strand conformation polymorphism analysis of polymerase chain reaction products using originally designed oligoprimers. Ti...

Topics

Adenocarcinoma
Alanine
Amino Acid Sequence
Base Sequence
DNA Primers
DNA, Neoplasm
DNA-Binding Proteins
Exons
Genetic Variation
Histidine
Humans
Leucine
Male
Molecular Sequence Data
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Prostatic Neoplasms

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Identifiers

PMID: 8274409
DOI: 10.1016/0960-0760(93)90316-o

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8274409-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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