Article
Androgen receptor gene mutations in human prostate cancer.
The Journal of steroid biochemistry and molecular biology - 1 Dec 1993
Suzuki H, Sato N, Watabe Y, Masai M, Seino S, Shimazaki J
Abstract excerpt
To investigate the structural abnormality of the androgen receptor (AR) in human prostate cancers, exons B-H encoding DNA- and hormone-binding domains were examined by single-strand conformation polymorphism analysis of polymerase chain reaction products using originally designed oligoprimers. Tissues from 7 cases of untreated stage B prostate cancer surgically removed and from 8 cases of endocrine...
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