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Article

Alterations of the retinoblastoma gene in human prostate adenocarcinoma

1 Feb 1996

Abstract excerpt

The loss or mutational inactivation of the RB1 tumor suppressor gene has been implicated in the development of a diverse group of human malignancies. However, the contribution of the RB1 gene alteration to human prostatic carcinogenesis has been poorly understood. Thus far, deletion of the promoter sequence and exon 21 from one primary tumor specimen and the alterations found in the cell line DU-145, are the only...

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Identifiers

PMID: 8834174
DOI: 10.1002/(sici)1098-2264(199602)15:2<108::aid-gcc5>3.0.co;2-7

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Source receipt: pubmed, retrieved 7 Sept 2026.

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