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Article

Histone H1 null vertebrate cells exhibit altered nucleosome architecture.

Nucleic acids research - 1 Jun 2010

Hashimoto Hideharu, Takami Yasunari, Sonoda Eiichiro, Iwasaki Tomohito, Iwano Hidetomo, Tachibana Makoto, Takeda Shunichi, Nakayama Tatsuo, Kimura Hiroshi, Shinkai Yoichi

Abstract excerpt

In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form nucleosomes, and chromatin fibers are thought to be stabilized by linker histones of the H1 type. Higher eukaryotes express multiple variants of histone H1; chickens possess six H1 variants. Here, we generated and analyzed the phenotype of a complete deletion of histone H1 genes in chicken cells. The H1-null cells showed decreased...

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Identifiers

PMID: 20156997
DOI: 10.1093/nar/gkq076
PMCID: PMC2887950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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