Article
Signatures of Specific DNA Binding by the AT-Rich Interaction Domain of BAF250a.
Biochemistry - 14 Jan 2020
Giri Malyasree, Maulik Aditi, Singh Mahavir
Abstract excerpt
The AT-rich interaction domain (ARID) containing BAF250a is a subunit of the BAF-A class of SWI/SNF chromatin remodeling complexes. The ARID belongs to a family of conserved DNA binding domains found in several eukaryotic proteins; however, its exact contribution to BAF250a function and the mechanism of its DNA binding are not well understood. Here we have probed the interaction of the BAF250a ARID with three...
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