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Article

The effect on cell phenotype of the mutagenic peptide of herpes simplex virus type-1.

European journal of cancer. Part B, Oral oncology - 1 Jul 1995

Das C M, Murrah V A, Zhang S, Wong G, Gilchrist E P, Shillitoe E J

Abstract excerpt

The transforming region of the genome of herpes simplex virus type-1 (HSV-1) encodes a peptide that raises the mutation frequency of cells. To find the effect of this peptide on cell phenotype, three types of cells were transfected with a shuttle vector plasmid that expressed the peptide. When immortalised rat fibroblasts were transfected they rapidly became anchorage-independent with high efficiency, but were...

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Identifiers

PMID: 7492925
DOI: 10.1016/0964-1955(95)00020-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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