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Article

Differential effects of p53 mutants on the growth of human bronchial epithelial cells.

Molecular carcinogenesis - 1 Jul 1997

Coursen J D, Bennett W P, Khan M A, Forrester K, Pietenpol J A, Harris C C

Abstract excerpt

We investigated the effects of five different p53 mutants on the growth of primary cultures of normal human bronchial epithelial (NHBE) cells. The five defective viral pZIP-Neo constructs contained the following mutations at mutational hot-spots found in human cancers: codons 143ala, 175his, 248trp, 249ser, and 273his. NHBE cells were infected with the p53 mutants, wild-type p53, or the pZIP-Neo vector control....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9254886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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