Article
Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment.
Radiation oncology investigations - 1 Jan 1997
Seymour C B, Mothersill C
Abstract excerpt
It has recently been shown that, when irradiated, human epithelial cells produce a factor or signal in the culture medium that can reduce the clonogenic survival of unirradiated cells. The mechanism is unknown, as is the nature of the signal or substance. In this paper, we show that the medium fr...
Topics
- Carcinoma
- Cell Death
- Cell Division
- Cell Survival
- Cells, Cultured
- Cobalt Radioisotopes
- Colonic Neoplasms
- Culture Media, Conditioned
- Cytoplasm
- DNA Damage
- Dose-Response Relationship, Radiation
- Environmental Exposure